The STAGES's Action Plan at the University of Milan is marked by the underlying idea of triggering structural change and promoting equal opportunities in science by fostering gender equality in career paths and by 'gendering', at the same time, the contents and methods of scientific research. The tailored Action Plan at UMIL was drafted after carefully taking stock of previous initiatives on equal opportunities implemented at UMIL’s, gathering data on female and male presence in research at all levels and after a detailed analysis of contextual constraints and opportunities. The Plan targets the Faculty of Food and Agricultural Sciences and the Faculty of Medicine, both exhibiting peculiarities in terms of size as well as type of horizontal and vertical segregation that make them ideal settings for intervention. However, it also includes actions targeting the whole University. The Action Plan is implemented under the coordination of the Interdepartmental Centre “Women and Gender Differences” and includes actions grouped in three main strategic areas: